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Which tests are primary indicators of kidney function?

  1. CRE and GFR

  2. Urea and Creatinine

  3. BUN and Creatinine

  4. Uric acid and BUN

The correct answer is: BUN and Creatinine

The primary indicators of kidney function are blood urea nitrogen (BUN) and creatinine. Both substances are waste products filtered out of the blood by the kidneys, and their levels provide important information about how well the kidneys are functioning. When evaluating kidney function, a significant increase in the levels of BUN and creatinine suggests that the kidneys are not effectively filtering these wastes from the bloodstream, indicating potential kidney impairment or disease. While other tests, such as creatinine clearance (which is related to the glomerular filtration rate or GFR) and urea, may also provide valuable information regarding kidney health, BUN and creatinine are the most commonly used and reliable indicators in clinical practice for assessing kidney function.